Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Dyschezia | Colonic Inertia
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00418Cetirizine hydrochloride--
BADD_D00422Cetuximab--
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00426Chenodiol--
BADD_D00432Chlordiazepoxide--
BADD_D00433Chlordiazepoxide hydrochloride--
BADD_D00442Chlorothiazide--
BADD_D00443Chlorothiazide sodium--
BADD_D00444Chlorphenamine--
BADD_D00445Chlorpromazine--
BADD_D00446Chlorpromazine hydrochloride--
BADD_D00448Chlorthalidone0.000769%
BADD_D00451Cholestyramine--
BADD_D00452Cholestyramine resin--
BADD_D00455Choline fenofibrate--
BADD_D00456Choline magnesium trisalicylate--
BADD_D00463Cidofovir--
BADD_D00464Cidofovir dihydrate--
BADD_D00465Cilazapril monohydrate--
BADD_D00467Cimetidine--
BADD_D00469Cinacalcet hydrochloride--
BADD_D00471Ciprofloxacin--
BADD_D00472Ciprofloxacin hydrochloride--
BADD_D00474Cisplatin0.009591%
BADD_D00475Citalopram--
BADD_D00476Citalopram hydrobromide--
BADD_D00479Cladribine--
BADD_D00480Clarithromycin--
BADD_D00481Clemastine fumarate--
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